Capacidade de exercício em pacientes com síndrome da apneia obstrutiva do sono

Daiana Moreira Mortari, Camila Pereira Leguisamo, Simone Chaves Fagondes

Resumo


A associação entre Síndrome da Apneia Obstrutiva do Sono (SAOS) e capacidade de exercício ainda não está bem determinada. Entretanto, sabe-se que muitos indivíduos portadores de SAOS apresentam respostas limitadas ao exercício físico. Tal achado, dentre outros fatores, pode estar relacionado à má qualidade de sono que acarreta, principalmente, sonolência diurna excessiva. O presente estudo objetivou realizar uma revisão de literatura sobre a capacidade de exercício em pacientes com SAOS. A estratégia de busca contemplou as bases de dados Pubmed, LILACS e SciELO. Foram realizadas três buscas em cada uma das bases, com as seguintes combinações de termos: “apneia” e “exercise” e “capacity”, “apnea” e “exercise” e “CPAP” e “apnea” e “cardiopulmonary” e “test”. Dos 108 artigos encontrados através da busca, 24 preencheram os critérios de inclusão do estudo e foram, então, analisados. Conclui-se que a capacidade física parece estar reduzida em pacientes com SAOS, estando o tratamento através de CPAP associado a uma melhora no desempenho físico.

 


Palavras-chave


apneia do sono tipo obstrutiva; tolerância ao exercício; frequência cardíaca

Texto completo:

PDF

Referências


American Academy of Sleep Medicine. International Classification of Sleep Disorders: diagnostic and coding manual. 2nd ed. Westchester: American Academy of Sleep Medicine; 2005.

Davies RJO, Stradling JR. The epidemiology of sleep apnoea. Thorax. 1996;51(Suppl 2):S65-S70.

Tufik S, Santos-Silva R, Taddei JA, Bittencourt LRA. Obstructive sleep apnea syndrome in the Sao Paulo epidemiologic sleep study. Sleep Med. 2010;11(5):441-6.

Siccoli MM, Pepperell JC, Kohler M, Craig SE, Davies RJ, Stradling JR. Effects of continuous positive airway pressure on quality of life in patients with moderate to severe obstructive sleep apnea: data from a randomized controlled trial. Sleep. 2008;31:1551-8.

Drager LF, Ladeira RT, Brandäo-Neto, RA, Lorenzi-Filho G, Benseñor IM. Síndrome da apneia obstrutiva do sono e sua relação com a hipertensão arterial sistêmica: evidências atuais. Arq Bras Cardiol. 2002;78:531-6.

Bassetti CL. Sleep and stroke. Semin Neurol. 2005;25:19-32.

Tasali E, Mokhlesi B, Van Cauter E. Obstructive sleep apnea and type 2 diabetes: interacting epidemics. Chest. 2008;133(2):496-506.

Fritscher LG, Canani S, Mottin CC, Fritscher CC, Berleze D, Chapman K, et al. Bariatric surgery in the treatment of obstructive sleep apnea in morbidly obese patients. Respiration. 2007;74:647-52.

American Thoracic Society. American College of Chest Physicians. ATS/ACCP statement on cardiopulmonary exercise testing. Am J Respir Crit Care Med. 2003;167:211-77.

Hargens TA, Guill SG, Zedalis D, Gregg JM, Nickols-Richardson SM, Herbert WG. Attenuated heart rate recovery following exercise testing in overweight, young men with untreated obstructive sleep apneia. Sleep. 2008;31(1):104-10.

Larsson BW, Kadi F, Ulfberg J, Aulin KP. Skeletal muscle morphology and aerobic capacity in patients with obstructive sleep apnoea syndrome. Respiration. 2008;76:21-7.

Lin CC, Hsieh WY, Chou CS, Liaw SF. Cardiopulmonary exercise testing in obstructive sleep apnea syndrome. Respir Physiol Neurobiol. 2006;150(1):27-34.

Neder JA, Nery LE. Teste de exercício cardiopulmonar. J Pneumol. 2002; 28(Supl 1):S166–206.

Nanas S, Sakellariou D, Kapsimalakou S, Dimopoulos S, Tassiou A, Tasoulis A, et al. Heart rate recovery and oxygen kinetics after exercise in obstructive sleep apnea syndrome. Clin Cardiol. 2010;33(1):46-51.

Ucok K, Aycicek A, Sezer M, Genc A, Akkaya M, Caglar V, et al. Aerobic and anaerobic exercise capacities in obstructive sleep apneia and associations with subcutaneous fat distributions. Lung. 2009;187(1):29-36.

Kaleth AS, Chittenden TW, Hawkins BJ, Hargens TA, Guill SG, Zedalis D, et al. Unique cardiopulmonary exercise test responses in overweight middle-aged adults with obstructive sleep apneia. Sleep Med. 2007;8(2):160-8.

Cintra F, Poyares D, Rizzi CF, Risso TT, Skomro R, Montuori E, et al. Cardiorespiratory response to exercise in men and women with obstructive sleep apnea. Sleep Med. 2009;10(3):368-73.

Alonso-Fernandez A, Garcia-Rio F, Arias MA, Mediano O. Obstructive sleep apnoea-hypoapnoea syndrome reversibly depresses cardiac response to exercise. Eur Heart J. 2006;27:207-15.

Rizzi CF, Cintra F, Risso T, Pulz C, Tufik S, De Paola A, Poyares D. Exercise capacity and obstructive sleep apneia in lean subjects. Chest. 2010; 137(1):109-14.

Alameri H, Al-Kabab Y, BaHammam A. Submaximal exercise in patients with severe obstructive sleep apneia. Sleep Breath. 2010;14:145-51.

Vanhecke TE, Franklin BA, Zalesin KC, Sangal RB, deJong AT, Agrawal V, et al. Cardiorespiratory fitness and obstructive sleep apneia syndrome in morbidly obese patients. Chest. 2008;134(3):539-45.

Przybylowski T, Bielicki P, Kumor M, Hildebrand K, Maskev-Warzechowska M, Korczvnski P, et al. Exercise capacity in patients with obstructive sleep apnea syndrome. J Physiol Pharmacol 2007; 58(Suppl 5): 563-574.

Meneghelo RS, Araújo CGS, Stein R, Mastrocolla LE, Albuquerque PF, Serra SM. III Diretrizes da Sociedade Brasileira de Cardiologia sobre teste ergométrico. Arq Bras Cardiol. 2010;95(5):1-26.

Tryfon S, Stanopoulos I, Dascalopoulou E, Argyropoulou P, Bouros D, Mavrofridis E. Sleep apnea syndrome and diastolic blood pressure elevation during exercise. Respiration. 2004;71(5):499-504.

Lin CC, Lin CK,Wu KM, Chou CS. Effect of treatment by nasal CPAP on cardiopulmonary exercise test in obstructive sleep apnea syndrome. Lung 2004;182:199–212.

Pendharkar SR, Tsai WH, Eves ND, Ford GT, Davidson WJ. CPAP increases exercise tolerance in obese subjects with obstructive sleep apnea. Respir Med. 2011;105(10):1565-71.

Egea CJ, Aizpuru F, Pinto JA, Ayuela JM, Ballester E, Zamarrón C, et al. Cardiac function after CPAP therapy in patients with chronic heart failure and sleep apnea: a multicenter study. Sleep Med. 2008;9(6):660-6.

Maeder MT, Ammann P, Münzer T, Schoch OD, Korte W, Hürny C et al. Continuous positive airway pressure improves exercise capacity and heart rate recovery in obstructive sleep apnea. Int J Cardiol. 2009;132(1):75–83.

Taguchi O, Hida W, Okabe S, Ebihara S, Ogawa H, Kikuchi Y, et al. Improvement of exercise performance with short-term nasal continuous positive airway pressure in patients with obstructive sleep apnea. Tohoku J. Exp Med. 1997;183:45-53.

Ackel-D'Elia C, da Silva AC, Silva RS, Truksinas E, Sousa BS, Tufik S, et al. Effects of exercise training associated with continuous positive airway pressure treatment in patients with obstructive sleep apnea syndrome. Sleep Breath. 2011;16(3):723-35.

Ueno LM, Drager LF, Rodrigues ACT, Rondon MUPB, Braga AM, Mathias W Jr et al. Effects of exercise training in patients with chronic heart failure and sleep apnea. Sleep. 2009;32(5):637-47.

Sengul YS, Ozalevli S, Oztura I, Itil O, Baklan B, et al. The effect of exercise on obstructive sleep apnea: a randomized and controlled trial. Sleep Breath. 2011;15:49-56.

Barnes M, Goldsworthy UR, Cary BA, Hill CJ. A diet and exercise program to improve clinical outcomes in patients with obstructive sleep apnea - a feasibility study. J Clin Sleep Med. 2009;5:409-15.

Giebelhaus V, Strohl KP, Lormes W, Lehmann M, Netzer N. Physical Exercise as an Adjunct Therapy in Sleep Apnea-An Open Trial. Sleep Breath. 2000;4(4):173-6.

Peppard PE, Young T. Exercise and sleep-disordered breathing: an association independent of body habitus. Sleep. 2004;27:480-4.

Basta M, Lin HM, Pejovic S, Sarrigiannidis A, Bixler E, Vgontzas AN. Lack of regular exercise, depression, and degree of apnea are predictors of excessive daytime sleepiness in patients with sleep apnea: sex differences. J Clin Sleep Med. 2008;4(1):19-25.


Métricas do artigo

Carregando Métricas ...

Metrics powered by PLOS ALM

Apontamentos

  • Não há apontamentos.




Direitos autorais



Apoio: ..............................................................................................................................................

    

Fundação São Paulo - Hospital universitário

 



 

Rev. Fac. Ciênc. Méd. Sorocaba, Sorocaba, SP, Brasil, e-ISSN 1984-4840

A Revista da Faculdade de Ciências Médicas de Sorocaba está licenciada com uma Licença Creative Commons - Atribuição 4.0 Internacional.