Insecticidal effect of Cannabis: a systematic review of toxicity on medically  important insects

Millena Fernandes; Edenilson Osinski Francisco; Renan Konig  Leal; Caroline Pereira Vieira; Wellyngton Vieira Eufrazio; Linério Ribeiro de Novais Júnior; Suelen de Souza Ramos; Rafael  Bitencourt; Gislaine Tezza Rezin; Josiane  Somariva Prophiro

doi:10.23925/1984-4840.2024v26a18

Authors

Millena Fernandes Universidade do Sul de Santa Catarina (UNISUL), campus Tubarão
Edenilson Osinski Francisco Universidade Estadual de São Paulo, campus Botucatu
Renan Konig Leal Universidade do Sul de Santa Catarina (UNISUL), campus Tubarão
Caroline Pereira Vieira Universidade do Sul de Santa Catarina (UNISUL), campus Tubarão
Wellyngton Vieira Eufrazio Universidade do Sul de Santa Catarina (UNISUL), campus Tubarão
Linério Ribeiro de Novais Júnior Universidade do Sul de Santa Catarina (UNISUL), campus Tubarão
Suelen de Souza Ramos Universidade do Sul de Santa Catarina (UNISUL), campus Tubarão
Rafael Bitencourt Universidade do Sul de Santa Catarina (UNISUL), campus Tubarão
Gislaine Tezza Rezin Universidade do Sul de Santa Catarina (UNISUL), campus Tubarão
Josiane Somariva Prophiro Universidade do Sul de Santa Catarina (UNISUL), campus Tubarão

DOI:

https://doi.org/10.23925/1984-4840.2024v26a18

Keywords:

Insect Vectors, Larva, Oils, Volatile, Cannabis, Toxicity

Abstract

Currently, there is a need for the development of vector insect control products that are ecologically viable, utilizing active principles available in nature. Natural compounds with insecticidal potential already identified in Cannabis are promising prospects for the control and management of vector arthropods of diseases. In this context, the work aims to investigate
possible disparities in the toxicity effects of Cannabis in different formulations and at different stages of the vectors' life. This is a systematic review. Experimental studies describing the toxic effects of Cannabis on eggs, larvae, pupae, and adult vector insects were included. Articles in which the insect was characterized as a mechanical vector, literature review research, and ethnobotanical studies were excluded. The study revealed the potential insecticidal effect of Cannabis when applied in different formulations on Ctenocephalides felis felis, Aedes albopictus, Anopheles stephensi, Anopheles gambiae, and Culex quinquefasciatus at different stages of development. Cannabis proved to be a promising plant in terms of mortality and evidenced effects on insect fertility, birth rates, and adult emergence. The study revealed a potential insecticidal effect of Cannabis. However, further investigations are crucial to elucidate the role of this plant in vector insect control strategies.

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