Novos aspectos diagnósticos da doença celíaca
Palavras-chave:
doença celíaca, diagnóstico precoce, glútensResumo
A doença celíaca é uma intolerância permanente ao glúten caracterizada por inflamação da mucosa, atrofia vilosa e hiperplasia das criptas do intestino delgado, com consequente má-absorção nutricional em indivíduos geneticamente suscetíveis. Sua prevalência varia de 0,5% a 5,6% em diferentes regiões. Tendo em vista ainda haver discussões quanto ao seu diagnóstico, os autores relatam neste artigo as atualizações na literatura sobre o diagnóstico clínico e laboratorial da doença celíaca.
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Kagnoff MF. Celiac disease: pathogenesis of a model immunogenetic disease. J Clin Invest. 2007; 117(1):41-9.
Dubé C, Rostom A, Sy R, Cranney A, Saloojee N, Garritty C, et al. The prevalence of celiac disease in avarage-risk and at-risk Western European populations: a sistematic review. Gastroenterology. 2005; 128(Suppl 1):S57-S67.
Accomando S, Cataldo F. The global village of celiac disease. Dig Liver Dis 2004; 36:492-8.
Oliveira RP, Sdepanian VL, Barreto JA, Cortez AJ, Carvalho FO, Bordin JO, et al. High prevalence of celiac disease in Brazilian blood donor volunteers based on screening by IgA antitissue transglutaminase antibody. Eur J Gastroenterol Hepatol. 2007; 19:43-9.
Ciclitira PJ. AGA technical review on celiac sprue. Gastroenterology. 2001; 120:1526-40.
Ciclitira PJ, Ellis HJ. Celiac disease. In: Yamada T, Alpers DH, Kaplowitz N, Laine L, Owyang C, Powell DW, editores. Textbook of Gastroenterology. 4th ed. Philadelphia: Lippincott Williams & Wilkins; 2003. p. 1580-98.
Nisticò L, Fagnani C, Coto I, Percopo S, Cotichini R, Limongelli MG, Paparo F, et al. Concordance, disease progression, and heritability of coeliac disease in Italian twins. Gut. 2006; 55(6):803-8.
Bethune MT, Khosla C. Parallels between pathogens and gluten peptides in celiac sprue. PLoS Pathog. 2008; 4(2):1-16.
Tursi A, Brandimarte G, Giorgetti GM, Elisei W, Inchingolo CD, Monardo E, et al. Endoscopic and histological findings in the duodenum of adults with celiac disease before and after changing to a gluten free diet: a 2-year prospective study. Endoscopy. 2006; 38:702-7.
Rostom A, Murray JA, Kagnoff MF. American Gastroenterological Association (AGA) Institute technical review on the diagnosis and management of celiac disease. Gastroenterology. 2006; 131(6):1981-2002.
Gama e Silva TS, Furlanetto TW. Diagnóstico de doença celíaca em adultos. Rev Assoc Med Bras. 2010; 56(1):122-6.
Cassol CA, Pellegrin CP, Wahys MLC, Pires MMS, Nassar SM. Perfil clínico dos membros da associação dos celíacos do Brasil: Regional de Santa Catarina (ACELBRA-SC). Arq Gastroenterol. 2007; 44(3):257-65.
Siqueira Neto JI, Costa ACLV, Magalhães FG, Silva GS. Neurological manifestations of celiac disease. Arq Neuropsiquiatr. 2004; 62(4):969-72.
Cardoso H, Teixeira AV, Machado AS, Vale AMH, Cruz D, Veloso FT. Doença celíaca manifestada no puerpério. J Port Gastrenterol. 2006; 13:47-50.
Farrell RJ, Kelly CP. Diagnosis of celiac sprue. Am J Gastroenterol. 2001; 96:3237-46.
Romaldini CC, Barbieri D. Anticorpos séricos na doença celíaca. Arq Gastroenterol. 1999; 36(4):258-64.
Lepers S, Couignoux S, Colombel JF, Dubucquoi S. Celiac disease in adults: new aspects. Rev Med Interne. 2004; 25:22-34.
Tursi A, Brandimarte G, Giorgetti GM, Gigliobianco A, Lombardi D, Gasbarrini G. Low prevalence of antigliadin and anti-endomysium antibodies in subclinical/silent celiac disease. Am J Gastroenterol. 2001; 96:1507-10.
Lewis NR, Scott BB. Systematic review: the use of serology to exclude or diagnose coeliac disease (a comparison of the endomysial and tissue transglutaminase antibody tests). Aliment Pharmacol Ther. 2006; 24:47-54.
Shamir R, Hernell O, Leshno M. Cost-effectiveness analysis of screening for celiac disease in the adult population. Med Decis Making. 2006; 26:282-93.
Green PH, Cellier C. Celiac disease. N Engl J Med. 2007; 357(17):1731-43.
Pais WP, Duerksen DR, Pettigrew NM, Bernstein CN. How many duodenal biopsy specimens are required to make a diagnosis of celiac disease? Gastrointest Endosc. 2008; 67(7):1082-7.
UEGW 2001 Working Group on Coeliac Disease. When is a coeliac a coeliac? Eur J Gastroenterol Hepatol. 2001; 13:1123-8.
AGA Institute Medical Position Statement on the Diagnosis and Management of Celiac Disease. Gastroenterology. 2006;131(6):1977-80.
Rewers M, Liu E, Simmons J, Redondo MJ, Hoffenberg EJ. Celiac disease associated with type 1 diabetes mellitus. Endocrinol Metab Clin North Am. 2004; 33(1):197-214.
Duggan JM. Coeliac disease: the great imitator. Med J Aust. 2004; 180: 524-6.
Tursi A, Brandimarte G, Giorgetti GM, Elisei W, Inchingolo CD, Monardo E, et al. Endoscopic and histological findings in the duodenum of adults with celiac disease before and after changing to a gluten free diet: a 2-year prospective study. Endoscopy. 2006; 38:702-7.
Horoldt BS, McAlindon ME, Stephenson TJ, Hadjivassiliou M, Sanders DS. Making the diagnosis of coeliac disease: is there a role for push enteroscopy? Eur J Gastroenterol Hepatol. 2004; 16:1143-6.
Hopper AD, Sidhu R, Hurlstone DP, McAlindon ME, Sanders DS. Capsule endoscopy: an alternative to duodenal biopsy for the recognition of villous atrophy in coeliac disease? Dig Liver Dis. 2007; 39(2):140-5.
Biagi F, Rondonotti E, Campanella J, Villa F, Bianchi PI, Klersy C, et al. Video capsule endoscopy and histology for small-bowel mucosa evaluation: a comparison performed by blinded observers. Clin Gastroenterol Hepatol. 2006; 4(8):998-1003.
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