Organização temporal da fala em três condições neurológicas relacionadas aos núcleos da base

Autores

  • Thais Helena Machado UFMG
  • Ana Cláudia Pereira Bertolino UFMG
  • Leandro Alves Pereira UFU
  • Francisco Eduardo Costa Cardoso UFMG
  • Rui Rothe-Neves UFMG

DOI:

https://doi.org/10.1590/1678-460x202258946

Palavras-chave:

dysarthria; speech acoustics; articulation disorders; movement disorders; phonetics

Resumo

Os núcleos da base participam de redes neuronais que controlam movimentos voluntários do corpo, incluindo os da fala. Doenças que afetam a função dessas estruturas podem gerar movimentos anormais hipocinéticos ou hipercinéticos, influenciando o controle motor da fala. Como a organização temporal prosódica varia na disartria devido à doença de Parkinson (DP), doença de Huntington (DH) e coreia de Sydenham (SC)? Três grupos clínicos (DP com e sem medicação, HD e SC) de 15 participantes e um grupo controle (n = 18) leram um texto em voz alta. As medidas de fluência da fala foram relacionadas aos limites sintáticos dentro do texto. Não houve correlação entre escalas motoras globais e parâmetros temporais de fala. Houve correlações entre os limites sintáticos e a duração das pausas em todos os grupos. Apenas os resultados de HD diferenciaram-se dos demais grupos clínicos e em relação ao grupo controle. Os grupos clínicos foram mais lentos na produção da fala, mas preservam a função sintática da prosódia em diferentes níveis. A disfunção dos núcleos da base parece afetar todos os grupos clínicos, apesar da etiologia.

Referências

Angelis, E. C. (2006). Voz e deglutição na doença de Parkinson. In L. A. F. Andrade, E. R. Barbosa, F. Cardoso, & H. A. G. Teive (Eds.), Doença de Parkinson: estratégias atuais do tratamento (pp. 197-207). Segmento Farma.

Angelis, E. C., Irineu, R. A., & Vilanova, L. C. P. (1997). Coréia de Sydenham - Avaliação fonoarticulatória. Pró Fono, 9(2), 17-21. Azevedo, L. L. (2001). Aspectos prosódicos da fala do parkinsoniano

[Master thesis]. Federal University of Minas Gerais.

Azevedo, L. L. (2007). Expressão da atitude através da prosódia em indivíduos com doença de Parkinson idiopática [Doctoral

dissertation]. University of Minas Gerais.

Azevedo, L. L., Cardoso, F., & Reis, C. (2003). Análise acústica da

prosódia em mulheres com doença de Parkinson: comparação com controles normais. Arquivos de Neuro-Psiquiatria, 61(4), 999-1003. https://doi.org/10.1590/s0004-282x2003000600021.

Barkmeier-Kraemer, J. M., & Clark, H. M. (2017). Speech-language pathology evaluation and management of hyperkinetic disorders affecting speech and swallowing function. Tremor and Other Hyperkinetic Movements, 7, 489. https://doi.org/10.5334/tohm.381.

Beato, R., Maia, D. P., Teixeira, A. L., & Cardoso, F. (2010). Executive functioning in adult patients with Sydenham’s chorea. Movement Disorders, 25(7), 853-857. https://doi.org/10.1002/mds.23154.

Boersma, P. W., & Weenink, D. (2009). Praat: doing phonetics by computer [Computer software]. http://www.praat.org/.

Brabenec, L., Mekyska, J., Galaz, Z., & Rektorova, I. (2017). Speech disorders in Parkinson’s disease: Early diagnostics and effects of medication and brain stimulation. Journal of Neural Transmission, 124(3), 303-334.

https://doi.org/10.1007/s00702-017-1676-0.

Bunton, K., Kent, R. D., Kent, J. F., & Rosenbek, J. C. (2000). Perceptuo-acoustic assessment of prosodic impairment in dysarthria. Clinical Linguistics & Phonetics, 14(1), 13-24. https://doi. org/10.1080/026992000298922.

Cardoso, F. (2009). Huntington disease and other choreas. Neurologic Clinics, 27(3), 719-736. https://doi.org/10.1016/j.ncl.2009.04.001.

Cardoso, F., Eduardo, C., Silva, A. P., & Mota, C. C. C. (1997). Chorea in fifty consecutive patients with rheumatic fever. Movement Disorders, 12(5), 701-703. https://doi.org/10.1002/mds.870120512.

Cardoso, F., Seppi, K., Mair, K. J., Wenning, G. K., & Poewe, W. (2006). Seminar on choreas. The Lancet Neurology, 5(7), 589-602. https:// doi.org/10.1016/s1474-4422(06)70494-x.

Cardoso, F., Vargas, A. P., Oliveira, L. D., Guerra, A. A., & Amaral, S. V. (1999). Persistent Sydenham’s chorea. Movement Disorders, 14(5), 805-807. https://doi.org/10.1002/1531-8257(199909)14:5<805::AID- MDS1013>3.0.CO;2-P.

Cavallieri, F., Budriesi, C., Gessani, A., Contardi, S., Fioravanti, V., Menozzi, E., Pinto, S., Moro, E., Valzania, F., & Antonelli, F. (2021). Dopaminergic treatment effects on dysarthric speech: Acoustic analysis in a cohort of patients with advanced Parkinson’s disease. Frontiers in Neurology, 11. 616062. https://doi.org/10.3389/ fneur.2020.616062.

Chan, J. C. S., Stout, J. C., & Vogel, A. P. (2019). Speech in prodromal and symptomatic Huntington’s disease as a model of measuring onset and progression in dominantly inherited neurodegenerative diseases. Neuroscience and Biobehavioral Reviews, 107, 450-460. https://doi. org/10.1016/j.neubiorev.2019.08.009.

Chu, S. Y., Barlow, S. M., Lee, J., & Wang, J. (2019). Effects of utterance rate and length on the spatiotemporal index in Parkinson’s disease. International Journal of Speech-Language Pathology, 22(2), 141-151. https://doi.org/10.1080/17549507.2019.1622781.

Cushnie-Sparrow, D., Adams, S., Abeyesekera, A., Pieterman, M., Gilmore, G., & Jog, M. (2018). Voice quality severity and responsiveness to levodopa in Parkinson’s disease. Journal of Communication Disorders, 76, 1-10. https://doi.org/10.1016/j.jcomdis.2018.07.003.

Darley, F. L. (1975). Diagnosis of motor speech disorders. Australian Journal of Human Communication Disorders, 3(1), 19-27. https:// doi.org/10.3109/asl2.1975.3.issue-1.03.

Darley, F. L., Aronson, A. E., & Brown, J. R. (1969). Differential diagnostic patterns of Dysarthria. Journal of Speech and Hearing Research, 12(2), 246-269. https://doi.org/10.1044/jshr.1202.246.

De Letter, M., Santens, P., Estercam, I., Van Maele, G., De Bodt, M., Boon, P., & Van Borsel, J. (2007). Levodopa‐induced modifications of prosody and comprehensibility in advanced Parkinson’s disease as perceived by professional listeners. Clinical Linguistics & Phonetics, 21(10), 783-791. https://doi.org/10.1080/02699200701538181.

Defebvre, L. (2005). La maladie de Parkinson. In C. Ozsancak, & P. Auzou (Eds.), Les troubles de la parole et de la déglutition dans la maladie de Parkinson (pp. 09-28). Solal.

Defebvre, L. (2007). La maladie de Parkinson et les syndromes parkinsoniens. In P. Auzou, V. Rolland-Monnoury, S. Pinto, & C. Ozsancak (Eds.), Les Dysarthries (pp. 165-168). Solal.

Diehl, S. K., Mefferd, A. S., Lin, Y.-C., Sellers, J., McDonell, K. E., de Riesthal, M., & Claassen, D. O. (2019). Motor speech patterns in Huntington disease. Neurology, 93(22), e2042-e2052. https://doi. org/10.1212/wnl.0000000000008541.

Duez, D. (2005). Organisation temporelle de la parole et dysarthrie parkinsonienne. In C. Ozsancak, & P. Auzou (Eds.), Les troubles de la parole et de la déglutition dans la maladie de Parkinson (pp. 195-213). Solal.

Duez, D. (2007). Proposition por une typologie et une évaluation acoustique des faits de dysprosodie. In P. Auzou, V. Rolland-Monnoury, S. Pinto, & C. Ozsancak (Eds.), Les Dysarthries (pp. 123-126). Solal.

Duffy, K., Paulsen, J. S., Beglinger, L. J., Langbehn, D. R., & Stout, J. C. (2007). Psychiatric symptoms in Huntington’s disease before diagnosis: The predict-HD study. Biological Psychiatry, 62(12), 1341-1346. https://doi.org/10.1016/j.biopsych.2006.11.034.

Efron, B., & Tibshirani, R. J. (1994). An introduction to the bootstrap. CRC.

Fabbri, M., Guimarães, I., Cardoso, R., Coelho, M., Guedes, L. C., Rosa, M. M., Godinho, C., Abreu, D., Gonçalves, N., Antonini, A., & Ferreira, J. J. (2017). Speech and voice response to a levodopa challenge in late-stage Parkinson’s disease. Frontiers in Neurology, 8. 432. https://doi.org/10.3389/fneur.2017.00432.

Fahn, S. E., & Members of UPDRS Development Committee. (1987). Unified Parkinson’s disease rating scale. In S. Fahn, C. Marsden, D. Calne, & M. Goldstein (Eds.), Recent developments in Parkinson’s disease (pp. 153-163). Macmillan.

Ferraz, H. B. (2006). Distúrbios do movimento. In K. Z. Ortiz (Ed.), Distúrbios Neurológicos adquiridos: fala e voz (pp. 125-143). Manole. Goberman, A. M., & Blomgren, M. (2003). Parkinsonian speech disfluencies: Effects of l-dopa-related fluctuations. Journal of Fluency Disorders, 28(1), 55-70.

https://doi.org/10.1016/s0094-730x(03)00005-6.

Goberman, A. M., & Coelho, C. (2002). Acoustic analysis of Parkinsonian

speech II: L-Dopa related fluctuations and methodological issues. NeuroRehabilitation, 17(3), 247-254. https://doi.org/10.3233/nre- 2002-17311.

Goberman, A. M., & Elmer, L. W. (2005). Acoustic analysis of clear versus conversational speech in individuals with Parkinson disease. Journal of Communication Disorders, 38(3), 215-230. https://doi. org/10.1016/j.jcomdis.2004.10.001.

Goberman, A., Coelho, C., & Robb, M. (2002). Phonatory characteristics of Parkinsonian speech before and after morning medication: The ON and OFF states. Journal of Communication Disorders, 35(3), 217-239.

https://doi.org/10.1016/s0021-9924(01)00072-7.

Goetz, C. G., Stebbins, G. T., Shale, H. M., Lang, A. E., Chernik, D. A., Chmura, T. A., Ahlskog, J. E., & Dorflinger, E. E. (1994). Utility of an objective dyskinesia rating scale for Parkinson’s disease: Inter- and intrarater reliability assessment. Movement Disorders, 9(4), 390-394. https://doi.org/10.1002/mds.870090403.

Group, H. S. (1996). Unified Huntington’s disease rating scale: Reliability and consistency. Movement Disorders, 11(2), 136-142. https://doi. org/10.1002/mds.870110204.

Hammen, V. L., & Yorkston, K. M. (1996). Speech and pause characteristics following speech rate reduction in hypokinetic dysarthria. Journal of Communication Disorders, 29(6), 429-445. https://doi.org/10.1016/0021-9924(95)00037-2.

Hammen, V. L., Yorkston, K. M., & Minifie, F. D. (1994). Effects of temporal alterations on speech intelligibility in parkinsonian dysarthria. Journal of Speech, Language, and Hearing Research, 37(2), 244-253. https://doi.org/10.1044/jshr.3702.244.

Hartelius, L., Carlstedt, A., Ytterberg, M., Lillvik, M., & Laakso, K. (2003). Speech disorders in mild and moderate Huntington disease: Results of dysarthria assessments of 19 individuals. Journal of Medical Speech- Language Pathology, 11, 1-15.

Hertrich, I., & Ackermann, H. (1994). Acoustic analysis of speech timing in Huntington′s disease. Brain and Language, 47(2), 182-196. https:// doi.org/10.1006/brln.1994.1048.

Hoff, J. I., van Hilten, B. J., & Roos, R. A. C. (1999). A review of the assessment of dyskinesias. Movement Disorders, 14(5), 737- 743. https://doi.org/10.1002/1531-8257(199909)14:5<737::AID- MDS1005>3.0.CO;2-A.

Hughes, A. J., Daniel, S. E., Kilford, L., & Lees, A. J. (1992). Accuracy of clinical diagnosis of idiopathic Parkinson’s disease: A clinico- pathological study of 100 cases. Journal of Neurology, Neurosurgery & Psychiatry, 55(3), 181-184. https://doi.org/10.1136/jnnp.55.3.181.

Illes, J. (1989). Neurolinguistic features of spontaneous language production dissociate three forms of neurodegenerative disease: Alzheimer’s, Huntington’s, and Parkinson’s. Brain and Language, 37(4), 628-642.

https://doi.org/10.1016/0093-934x(89)90116-8.

Lowit, A., Marchetti, A., Corson, S., & Kuschmann, A. (2018). Rhythmic performance in hypokinetic dysarthria: Relationship between reading, spontaneous speech and diadochokinetic tasks. Journal of Communication Disorders, 72, 26-39. https://doi.org/10.1016/j. jcomdis.2018.02.005.

Ludlow, C. L., Connor, N. P., & Bassich, C. J. (1987). Speech timing in Parkinson’s and Huntington’s disease. Brain and Language, 32(2), 195-214. https://doi.org/10.1016/0093-934x(87)90124-6.

Maia, D. P., Teixeira, A. L., Quintao Cunningham, M. C., & Cardoso, F. (2005). Obsessive compulsive behavior, hyperactivity, and attention deficit disorder in Sydenham chorea. Neurology, 64(10), 1799-1801. https://doi.org/10.1212/01.wnl.0000161840.62090.0e.

Martinez-Sánchez F. (2010). Speech and voice disorders in Parkinson’s disease. Revista de Neurologia, 51(9), 542-550.

McRae, P. A., Tjaden, K., & Schoonings, B. (2002). Acoustic and perceptual consequences of articulatory rate change in Parkinson disease. Journal of Speech, Language, and Hearing Research, 45(1), 35-50.

https://doi.org/10.1044/1092-4388(2002/003).

Meynadier, Y., Lagrue, B., Mignard, P., & Viallet, F. (1999). Effects of L-Dopa treatment on the production and perception of parkinsonian vocal intonation. Parkinsonism and Related Disorders, 5(Supplement 1), S121.

Mignard, P., Cavé, C., Lagrue, B., & Meynadier, Y. (2001). Étude expérimentale des pauses silencieuses chez les parkinsoniens en production orale spontanée et en lecture. Revue de Neuropsychologie, 11, 39-63.

Mourão, L. F. (2006). Intervenção fonoaudiológica nos distúrbios do movimento. In K. Z. Ortiz (Ed.), Distúrbios Neurológicos Adquiridos: fala e voz (pp. 144-160). Manole.

Mourão, L.F., & Ferraz, H.B. (2003). Avaliação e tratamento dos distúrbios do movimento. In I. J. A. Rios (Ed.), Conhecimentos essenciais para atender bem em fonoaudiologia hospitalar (pp. 125-139). Pulso.

Murray, L. L. (2000). Spoken language production in Huntington’s and Parkinson’s diseases. Journal of Speech, Language, and Hearing Research, 43(6), 1350-1366. https://doi.org/10.1044/jslhr.4306.1350.

Oliveira, P. M. (2003). Estudos prosódicos da fala dos portadores de coreia de Sydenham [Master thesis]. Federal University of Minas Gerais.

Oliveira, P. M., Cardoso, F., Maia, D. P., Cunningham, M. C. Q., Teixeira Jr, A. L., & Reis, C. (2010). Acoustic analysis of prosody in Sydenham’s chorea. Arquivos de Neuro-Psiquiatria, 68(5), 744-748. https://doi. org/10.1590/s0004-282x2010000500013.

Özsancak, C. (2007). La dysarthrie dans la maladie de Huntington. In P. Auzou, V. Rolland-Monnoury, S. Pinto, & C. Ozsancak (Eds.), Les Dysarthries (pp. 183-186). Solal.

Pah, N. D., Motin, M. A., Kempster, P., & Kumar, D. K. (2021). Detecting effect of levodopa in Parkinson’s disease patients using sustained phonemes. IEEE Journal of Translational Engineering in Health and Medicine, 9, 1-9. https://doi.org/10.1109/jtehm.2021.3066800.

Perini, M. A. (1996). A gramática descritiva do português. Ática. Perini, M. A. (2006). Princípios de linguística descritiva: Introdução aopensamento gramatical. Parábola.

Pinho, P., Monteiro, L., Soares, M. F. de P., Tourinho, L., Melo, A., &

Nóbrega, A. C. (2018). Impact of levodopa treatment in the voice pattern of Parkinson’s disease patients: a systematic review and meta- analysis. CoDAS, 30(5). e20170200.

Pinto, S. (2009). Intérêt de l’utilisation de la tomographie par émission de positrons pour l’étude de la parole normale et pathologique. In A. Marchal, & C. Cavé (Eds.), L’imagerie médicale pour l’etude de la parole (pp. 215-236). Lavoisier.

Pinto, S., Ghio, A., Teston, B., & Viallet, F. (2010). La dysarthrie au cours de la maladie de Parkinson. Histoire naturelle de ses composantes: Dysphonie, dysprosodie et dysarthrie. Revue Neurologique, 166(10), 800-810. https://doi.org/10.1016/j.neurol.2010.07.005.

Pinto, S., Ozsancak, C., Tripoliti, E., Thobois, S., Limousin-Dowsey, P., & Auzou, P. (2004). Treatments for dysarthria in Parkinson’s disease. The Lancet Neurology, 3(9), 547-556. https://doi.org/10.1016/s1474- 4422(04)00854-3.

Poluha, P.C., Teulings, H.L., & Brookshire, R.H. (1998). Handwriting and speech changes across the levodopa cycle in Parkinson’s disease. Acta Psychologica, 100(1-2), 71-84. https://doi.org/10.1016/s0001- 6918(98)00026-2.

Ramig, L. O., Fox, C., & Sapir, S. (2008). Speech treatment for Parkinson’s disease. Expert Review of Neurotherapeutics, 8(2), 297-309. https:// doi.org/10.1586/14737175.8.2.297.

Reis, C., Gama, A. C. C., Cardoso, F., Teixeira, E. G., & Pereira, L. A. (2007). Organisation temporelle dans la parole chez des malades brésiliens atteints de la maladie de Parkinson. Travaux Interdisciplinaires Du Laboratoire Parole et Langage d’Aix-En- Provence (TIPA), 26, 131-152.

Rigaldie, K., Nespoulou, J. L., & Vigouroux, N. (2004). La prosodie chez les sujets parkinsoniens: Analyse de la production de la gamme musicale. Revue Parole, 31, 375-408.

Rosen, K. M., Kent, R. D., Delaney, A. L., & Duffy, J. R. (2006). Parametric quantitative acoustic analysis of conversation produced by speakers with dysarthria and healthy speakers. Journal of Speech, Language, and Hearing Research, 49(2), 395-411. https://doi.org/10.1044/1092- 4388(2006/031).

Rosin, B., Nevet, A., Elias, S., Rivlin-Etzion, M., Israel, Z., & Bergman, H. (2007). Physiology and pathophysiology of the basal ganglia- thalamo-cortical networks. Parkinsonism & Related Disorders, 13, S437-S439. https://doi.org/10.1016/s1353-8020(08)70045-2.

Ross, C. A., Reilmann, R., Cardoso, F., McCusker, E. A., Testa, C. M., Stout, J. C., Leavitt, B. R., Pei, Z., Landwehrmeyer, B., Martinez, A., Levey, J., Srajer, T., Bang, J., & Tabrizi, S. J. (2019). Movement disorder society task force viewpoint: Huntington’s disease diagnostic categories. Movement Disorders Clinical Practice, 6(7), 541-546. https://doi.org/10.1002/mdc3.12808.

Rusz, J., Klempíř, J., Baborová, E., Tykalová, T., Majerová, V., Čmejla, R., Růžička, E., & Roth, J. (2013). Objective acoustic quantification of phonatory dysfunction in Huntington’s disease. PLoS ONE, 8(6), e65881. https://doi.org/10.1371/journal.pone.0065881.

Rusz, J., Klempíř, J., Tykalová, T., Baborová, E., Čmejla, R., Růžička, E., & Roth, J. (2014a). Characteristics and occurrence of speech impairment in Huntington’s disease: Possible influence of antipsychotic medication. Journal of Neural Transmission, 121(12), 1529-1539. https://doi.org/10.1007/s00702-014-1229-8.

Rusz, J., Saft, C., Schlegel, U., Hoffman, R., & Skodda, S. (2014b). Phonatory dysfunction as a preclinical symptom of Huntington disease. PLoS ONE, 9(11), e113412. https://doi.org/10.1371/journal. pone.0113412.

Rusz, J., Tykalová, T., Klempíř, J., Čmejla, R., & Růžička, E. (2016). Effects of dopaminergic replacement therapy on motor speech disorders in Parkinson’s disease: Longitudinal follow-up study on previously untreated patients. Journal of Neural Transmission, 123(4), 379-387. https://doi.org/10.1007/s00702-016-1515-8.

Sanabria, J., Ruiz, P. G., Gutierrez, R., Marquez, F., Escobar, P., Gentil, M., & Cenjor, C. (2001). The effect of levodopa on vocal function in Parkinson’s disease. Clinical Neuropharmacology, 24(2), 99-102. https://doi.org/10.1097/00002826-200103000-00006.

Sapir, S. (2014). Multiple factors are involved in the dysarthria associated with Parkinson’s disease: A review with implications for clinical practice and research. Journal of Speech, Language, and Hearing Research, 57(4), 1330-1343. https://doi.org/10.1044/2014_ jslhr-s-13-0039.

Sapir, S., Ramig, L., & Fox, C. (2008). Speech and swallowing disorders in Parkinson disease. Current Opinion in Otolaryngology & Head and Neck Surgery, 16(3), 205-210. https://doi.org/10.1097/ moo.0b013e3282febd3a.

Skodda, S., Flasskamp, A., & Schlegel, U. (2010). Instability of syllable repetition as a model for impaired motor processing: Is Parkinson’s disease a “rhythm disorder”? Journal of Neural Transmission, 117(5), 605-612.

https://doi.org/10.1007/s00702-010-0390-y.

Skodda, S., Grönheit, W., & Schlegel, U. (2011). Intonation and speech rate in Parkinson’s disease: General and dynamic aspects and responsiveness to levodopa admission. Journal of Voice, 25(4), e199-e205. https://doi.org/10.1016/j.jvoice.2010.04.007.

Skodda, S., Rinsche, H., & Schlegel, U. (2009). Progression of dysprosody in Parkinson’s disease over time - A longitudinal study. Movement Disorders, 24(5), 716-722. https://doi.org/10.1002/mds.22430.

Skodda, S., & Schlegel, U. (2008). Speech rate and rhythm in Parkinson’s disease. Movement Disorders, 23(7), 985-992. https://doi.org/10.1002/ mds.21996.

Skodda, S., Schlegel, U., Hoffmann, R., & Saft, C. (2014). Impaired motor speech performance in Huntington’s disease. Journal of Neural Transmission, 121(4), 399-407. https://doi.org/10.1007/s00702-013- 1115-9.

Spencer, K. A., & Rogers, M. A. (2005). Speech motor programming in hypokinetic and ataxic dysarthria. Brain and Language, 94(3), 347- 366. https://doi.org/10.1016/j.bandl.2005.01.008.

Tasset, I., Sánchez, F., & Túnez, I. (2009). Bases moleculares de la enfermedad de Huntington: Papel del estrés oxidativo. Revista de Neurologia, 49(8), 424-429. https://doi.org/10.33588/ rn.4908.2009192.

Teixeira, A. L., Cardoso, F., Maia, D., & Cunningham, M. (2003). Sydenham’s chorea may be a risk factor for drug induced parkinsonism. Journal of Neurology, Neurosurgery & Psychiatry, 74(9), 1350-1351. https://doi.org/10.1136/jnnp.74.9.1350-a.

Teixeira, A. L., Maia, D. P., & Cardoso, F. (2005). UFMG Sydenham’s chorea rating scale (USCRS): Reliability and consistency. Movement Disorders, 20(5), 585-591. https://doi.org/10.1002/mds.20377.

Teixeira, E. G. (2008). Organização temporal da leitura oral na doença de Parkinson [Master thesis]. Federal University of Minas Gerais.

Teston, B., & Viallet, F. (2005). La dysprosodie parkinsonienne. In C. Ozsancak, & P. Auzou (Eds.), Les troubles de la parole et de la déglutition dans la maladie de Parkinson (pp. 161-193). Solal.

Thobois, S., & Peisson, S. (2007). La maladie de Huntington: de la clinique à la thérapeutique. In P. Auzou, V. Rolland-Monnoury, S. Pinto, & C. Ozsancak (Eds.), Les Dysarthries (pp. 179-182). Solal.

Tjaden, K., & Wilding, G. E. (2004). Rate and loudness manipulations in dysarthria. Journal of Speech, Language, and Hearing Research, 47(4), 766-783. https://doi.org/10.1044/1092-4388(2004/058).

Tumas, V., Caldas, C. T., Santos, A. C., Nobre, A., & Fernandes, R. M. F. (2007). Sydenham’s chorea: Clinical observations from a Brazilian movement disorder clinic. Parkinsonism & Related Disorders, 13(5), 276-283. https://doi.org/10.1016/j.parkreldis.2006.11.010.

Velasco-García, M. J., Cobeta, I., Martín, G., Alonso-Navarro, H., & Jimenez-Jimenez, F. J. (2011). Acoustic analysis of voice in Huntington’s disease patients. Journal of Voice, 25(2), 208-217. https://doi.org/10.1016/j.jvoice.2009.08.007.

Viallet, F., Teston, B., Jankowski, L., Purson, A., Peragut, J., Regis, J., & Wiitjas, T. (2002). Effects of pharmacological versus electrophysiological treatments on parkinsonian dysprosody. In Proceedings of the Speech Prosody (pp. 679-682). Laboratoire Parole et Langage.

Viallet, F., Teston, B., Jankowski, L., Purson, A., Meynadier, Y., & Lagrue, B. (2003). Analyse acoustique de la production vocale: Contribution à l’évaluation de la dysprosodie parkinsonienne. Revue de Neurologie.

Viallet, F., & Teston, B. (2007). La dysarthrie dans la maladie de Parkinson. In P. Auzou, V. Rolland-Monnoury, S. Pinto, & C. Ozsancak. Les Dysarthries (pp. 169-174). Solal.

Vogel, A. P., Shirbin, C., Churchyard, A. J., & Stout, J. C. (2012). Speech acoustic markers of early stage and prodromal Huntington’s disease: A marker of disease onset? Neuropsychologia, 50(14), 3273-3278. https://doi.org/10.1016/j.neuropsychologia.2012.09.011.

Volkmann, J., Hefter H, Lange HW, & Freund HJ. (1992). Impairment of temporal organization of speech in basal ganglia diseases. Brain and Language, 43(3), 386-399. https://doi.org/10.1016/0093- 934x(92)90108-q.

Whitfield, J. A., Reif, A., & Goberman, A. M. (2017). Voicing contrast of stop consonant production in the speech of individuals with Parkinson disease ON and OFF dopaminergic medication. Clinical Linguistics & Phonetics, 32(7), 587-594. https://doi.org/10.1080/02699206.20 17.1387816.

Publicado

2023-09-09

Como Citar

Machado, T. H. ., Bertolino, A. C. P. ., Pereira , L. A. ., Cardoso, F. E. C. ., & Rothe-Neves, R. . (2023). Organização temporal da fala em três condições neurológicas relacionadas aos núcleos da base. DELTA: Documentação E Estudos Em Linguística Teórica E Aplicada, 38(3). https://doi.org/10.1590/1678-460x202258946