Long-latency auditory evoked potentials-verbal and cortical gain in patients with tinnitus
DOI:
https://doi.org/10.23925/2176-2724.2025v37i2e70256Keywords:
Tinnitus, Auditory Evoked Potentials, Adult, Central Nervous System, Auditory CortexAbstract
Objective: To analyze whether the presence of tinnitus can alter the amplitudes and the P2/P1 wave ratio in the cortical Long-Latency Auditory Evoked Potential (LLAEP) with verbal stimulus in young adults. Methodology: Observational, analytical, cross-sectional study with a convenience sample consisting of educated, right-handed patients without hearing loss and without auditory complaints other than tinnitus. Patients undergoing pharmacological treatment for tinnitus or presenting conditions that could compromise the research were excluded. Twenty individuals participated, divided into two groups: study group (SG) [7 women/5 men aged 19–35 years (mean = 24 years); 11 right ears and 12 left ears were evaluated; 11 cases of bilateral tinnitus and 1 case of unilateral tinnitus in the left ear]; control group (CG) [5 women/3 men aged 19–35 years (mean = 25 years); 8 right ears and 8 left ears were evaluated]. All participants underwent basic audiological assessment, central auditory processing evaluation, neuropsychological assessment, transient otoacoustic emissions, brainstem auditory evoked potential, and the LLAEP as the research procedure. Data analysis was performed using the Mann-Whitney U test, adopting a significance level of p ≤ 0.05. Results: Statistically significant differences were observed only for the P2 component in the left ear, with mean values of 4.42 for the control group and 6.39 for the study group (p = 0.017). Conclusion: The presence of tinnitus in young adults with normal audiometry was associated with higher amplitude of the P2 component in the LLAEP with verbal stimulus, specifically in the left ear. However, no significant changes were observed in the P2/P1 ratio between the groups.
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Copyright (c) 2025 Hélinton Goulart Moreira, Fabiana Cristina Toillier, Larissa Coradini, Bruna Ribas Maia, Rubens Jonatha dos Santos Ferreira, Michele Vargas Garcia
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