Comparison of medication-related fall risk in hospitalized adults and older people

systematic review and probable meta-analysis protocol

Authors

DOI:

https://doi.org/10.23925/2176-901X.2021v24i1p639-650

Keywords:

Aged, Drug Therapy, Accidental Falls

Abstract

The proposed study aims to verify whether drugs, drug classes, and polypharmacy related to the occurrence of falls are the same for hospitalized adults and older people. The present protocol was registered in the International Prospective Register of Systematic Reviews (PROSPERO) (ID: CRD42020208624). The search for articles will be carried out in PubMed, Embase, and in Latin American and Caribbean Literature on Health Sciences (Lilacs) databases. If quantitative analysis is not possible, a synthesis of the present information will be carried out.

Author Biographies

Amanda Pestana da Silva, Pontifícia Universidade Católica do Rio Grande do Sul

Graduation in Nursing, Pontifical Catholic University of Rio Grande do Sul. Master's degree in progress at the Graduate Program in Biomedical Gerontology. Postgraduate Nursing in Intensive Care and Adult Emergency, at Hospital Moinhos de Vento. Member of the Interdisciplinary Patient Safety Research Group. Member of the Artificial Intelligence in Health Group.

 

Carla Helena Augustin Scwanke, Pontifícia Universidade Católica do Rio Grande do Sul

Graduated in Medicine, Pontifical Catholic University of Rio Grande do Sul, PUCRS.  Specialist in Geriatrics from Hospital São Lucas, PUCRS. Master in Internal Medicine, area of ​​concentration in Geriatrics, PUCRS, CAPES scholarship holder) and PhD in Biomedical Gerontology, PUCRS3, CAPES scholarship holder). Professor at PUCRS since 2002. Adjunct professor TI / 40, at the School of Medicine, permanent professor at the Postgraduate Program in Biomedical Gerontology (PPG-GERONBIO), professor and researcher at the Institute of Geriatrics and Gerontology (IGG).

ORCID iD: https://orcid.org/0000-0002-0397-771X

Thiana Sebben Pasa, Pontifícia Universidade Católica do Rio Grande do Sul

Graduation in Nursing, Federal University of Santa Maria, UFSM/RS. Master's in Nursing, Graduate Program in Nursing at Federal University of Santa Maria UFSM (PPGEnf/UFSM), Brazil; and Doctoral Student at the Graduate Program in Biomedical Gerontology at the Pontifical Catholic University of Rio Grande do Sul (PUCRS-CAPES scholarship holder). Nurse at the Internal Regulation Nucleus/NIR- Bed Management, at the University Hospital of Santa Maria (HUSM/EBSERH). Professor at the Pontifical Catholic University of Rio Grande do Sul, Brazil. Graduate Program in Biomedical Gerontology.

ORCID iD: https://orcid.org/0000-0003-3931-4149

José Francisco Secorun Inácio, Univesidade Federal do Rio Grande do Sul

Degree in Electrical Engineering, Federal University of Rio Grande do Sul. Master in Health Research and Innovation Processes, Instituto de Cardiologia do Rio Grande do Sul. Currently works as an Engineer at Toth Lifecare, developing and executing tests of standards for electromedical equipment. In the academic field he has experience and publications performing Meta-analyses of Systematic Reviews.

ORCID iD: https://orcid.org/0000-0001-9799-7588

Ana Laura Olsefer Rotta, Pontifícia Universidade Católica do Rio Grande do Sul

Graduation in Nursing, Pontifical Catholic University of Rio Grande do Sul, PUCRS, Brazil. Monitor at the PUCRS.

 

Janete de Souza Urbanetto, Pontifícia Universidade Católica do Rio Grande do Sul

Graduation in Nursing, Master in Nursing, Doctor in Medicine and Health Sciences, Pontifical Catholic University of Rio Grande do Sul, PUCRS, Brazil. Adjunct Professor at the Pontifical Catholic University of Rio Grande do Sul, Brazil.

 

References

Agência Nacional de Vigilância Sanitária. (ANVISA, 2019). Relatório dos Estados - Eventos Adversos: Brasil. Brasília, DF: ANVISA. Retrieved July 30, 2020, from: https://www.gov.br/anvisa/pt-br/assuntos/servicosdesaude/notificacoes/notificacao-de-incidentes-eventos-adversos-nao-infecciosos-relacionados-a-assistencia-a-saude/relatorios-de-incidentes-eventos-adversos-relacionados-a-assistencia-a-saude.

Associação Nacional de Hospitais Privados. (ANPV, 2018). Manual de Gerenciamento e Assistência ao Idoso. Recomendações dos Hospitais da Associação Nacional de Hospitais Privados – Anahp. In: ANAHP. Retrieved July 30, 2020, from: https://www.anahp.com.br/noticias/conahp/anahp-lanca-manual-para-auxiliar-hospitais-na-implementacao-da-lgpd/.

de Vries, M., Seppala, L. J., Daams, J. G., van de Glind, E. M. M., Masud, T., van der Velde, N., & EUGMS Task and Finish Group on Fall-Risk-Increasing Drugs. (2018). Fall-Risk-Increasing Drugs: A Systematic Review and Meta-Analysis: I. Cardiovascular Drugs. J Am Med Dir Assoc, 19(4), 371.e371-371.e379. Retrieved July 30, 2020, from: https://doi.org/10.1016/j.jamda.2017.12.013.

Dyks, D., & Sadowski, C. A. (2015). Interventions to Reduce Medication-Related Falls. CGS Journal of CME, 5(1), 23-31. Retrieved July 30, 2020, from: http://www.rgpeo.com/media/69639/dyks%20article.pdf.

Hayden, J. A., van der Windt, D. A., Cartwright, J. L., Côté, P., & Bombardier, C. (2013). Assessing bias in studies of prognostic factors. Ann Intern Med, 158(4), 280-286. Retrieved July 30, 2020, from: https://doi.org/10.7326/0003-4819-158-4-201302190-00009.

Huguet, A., Hayden, J. A., Stinson, J., McGrath, P. J., Chambers, C. T., Tougas, M. E., & Wozney, L. (2013). Judging the quality of evidence in reviews of prognostic factor research: adapting the GRADE framework. Syst Rev, 2, 71. Retrieved July 30, 2020, from: https://doi.org/10.1186/2046-4053-2-71.

Instituto para práticas seguras no uso de medicamentos. (2017). Medicamentos associados à ocorrência de quedas. In (Vol. 6, pp. 6). Belo Horizonte, MG: ISMP Brasil. Retrieved July 30, 2020, from: https://www.ismp-brasil.org/site/wp-content/uploads/2019/02/615-boletim-ismp-fevereiro-2019.pdf.

Kohn, L. T., Corrigan, J. M., & Donaldson, M. S. (2000). To Err is Human: Building a Safer Health System. National Academy Press. Retrieved July 30, 2020, from: https://doi.org/10.17226/9728.

Liberati, A., Altman, D. G., Tetzlaff, J., Mulrow, C., Gøtzsche, P. C., Ioannidis, J. P. A., Clarke, M., Devereaux, P. J., Kleijnen, J., & Moher, D. (2009). The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: explanation and elaboration. BMJ, 339, b2700. Retrieved July 30, 2020, from: https://doi.org/10.1136/bmj.b2700.

McGowan, J., Sampson, M., Salzwedel, D. M., Cogo, E., Foerster, V., & Lefebvre, C. (2016). PRESS Peer Review of Electronic Search Strategies: 2015 Guideline Statement. J Clin Epidemiol, 75, 40-46. Retrieved July 30, 2020, from: https://doi.org/10.1016/j.jclinepi.2016.01.021.

National Academies of Sciences, E., and Medicine. (2018). Crossing the global quality chasm: Improving health care worldwide. National Academies Press. Retrieved July 30, 2020, from: http://www.ispro.ro/files/Crossing%20the%20Global%20Quality%20Chasm.%20Improving%20Health%20Care%20Worldwide%20(2018).pdf;

Ouzzani, M., Hammady, H., Fedorowicz, Z., & Elmagarmid, A. (2016). Rayyan — a web and mobile app for systematic reviews. Systematic Reviews, 5(210), 1-10. Retrieved July 28, 2020, from: https://systematicreviewsjournal.biomedcentral.com/track/pdf/10.1186/s13643-016-0384-4.

Seppala, L. J., Wermelink, A. M. A. T., de Vries, M., Ploegmakers, K. J., van de Glind, E. M. M., Daams, J. G., van der Velde, N., & EUGMS task and Finish group on fall-risk-increasing drugs. (2018). Fall-Risk-Increasing Drugs: A Systematic Review and Meta-Analysis: II. Psychotropics. J Am Med Dir Assoc, 19(4), 371.e311-371.e317. Retrieved July 30, 2020, from: https://doi.org/10.1016/j.jamda.2017.12.098.

Seppala, L. J., Wermelink, A. M. A. T., de Vries, M., Ploegmakers, K. J., van de Glind, E. M. M., Daams, J. G., van der Velde, N., & EUGMS Task and Finish Group on Fall-Risk-Increasing Drugs. (2018). Fall-Risk-Increasing Drugs: A Systematic Review and Meta-analysis: III. Others. J Am Med Dir Assoc, 19(4), 372.e371-372.e378. https://doi.org/10.1016/j.jamda.2017.12.099.

Shamseer, L., Moher, D., Clarke, M., Ghersi, D., Liberati, A., Petticrew, M., Shekelle, P., Stewart, L. A., & PRISMA-P Group. (2015). Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015: elaboration and explanation. BMJ, 350, g7647. https://doi.org/10.1136/bmj.g7647.

Silva, A. K. M., Costa, D. C. M. d., & Reis, A. M. M. (2019). Risk factors associated with in-hospital falls reported to the Patient Safety Commitee of a teaching hospital. Einstein (São Paulo), 17(1). http://dx.doi.org/ 10.31744/einstein_journal/2019AO4432.

World Health Organization. (2018). Ageing and Health: Fact Sheets. WHO Media Center. Retrieved June 12, 2019, from https://www.who.int/news-room/fact-sheets/detail/ageing-and-health.

Published

2022-01-24

How to Cite

Silva, A. P. da ., Scwanke, C. H. A. ., Pasa, T. S. ., Inácio, J. F. S. ., Rotta, A. L. O. ., & Urbanetto, J. de S. . (2022). Comparison of medication-related fall risk in hospitalized adults and older people: systematic review and probable meta-analysis protocol. Revista Kairós-Gerontologia, 24(1), 639–650. https://doi.org/10.23925/2176-901X.2021v24i1p639-650

Issue

Section

Papers