Cutaneous lupus erythematosus in a tertiary dermatologic center in Brazil
DOI:
https://doi.org/10.23925/1984-4840.2020v22i1a8Keywords:
lupus erythematosus, cutaneous, connective tissue diseases, prevalence, epidemiology, dermatology.Abstract
Objective: To evaluate the epidemiological situation of systemic lupus erythematosus in the state of Ceará in 2015. Method: This is a quantitative retrospective study, in which all records of medical consultations carried out at the Reference Center for Dermatology Dona Libânia (CDERM), Fortaleza, Ceará, in 2015, using the variables: name, gender, age, date of the consultation, medical record number, presumptive or confirmed diagnosis, other associated conditions and the patient’s frequency at CDERM (if the first time or when returning to the institution’s medical care). Results: Of the 19,576 patients analyzed, 320 patients were diagnosed with lupus, representing a prevalence of 1.63% in the service, of which 185 were diagnosed with discoid lupus. Conclusion: Cutaneous lupus is a disease of extreme importance and significant prevalence in our country, but it still lacks consistency of epidemiological data, requiring larger multicenter and epidemiological studies, both in Ceará and Brazil, for an adequate evaluation of the prevalence of this disease.
Downloads
Metrics
References
Jarukitsopa S, Hoganson DD, Crowson CS, Sokumbi O, Davis MD, Michet Jr CJ, et al. Epidemiology of systemic lupus erythematosus and cutaneous lupus erythematosus in a predominantly white population in the United States. Arthritis Care Res. 2015;67(6):817-28. https://doi.org/10.1002/acr.22502
Gilliam JN, Sontheimer RD. Distinctive cutaneous subsets in the spectrum of lupus erythematosus. J Am Acad Dermatol. 1981;4(4):471-5. https://doi.org/10.1016/s0190-9622(81)80261-7
Vargas KS, Romano MA. Lúpus eritematoso sistêmico: aspectos epidemiológicos e diagnóstico. Rev Salus. 2009;3(1):79-94.
Mota LMH, Haddad GP, Lima RAC, Carvalho JFd, Muniz-Junqueira MI, Neto S, et al. Lúpus induzido por drogas: da imunologia básica à aplicada. Rev Bras Reumatol. 2007;47(6):431-7. https://doi.org/10.1590/S0482-50042007000600007
Lee HJ, Sinha AA. Cutaneous lupus erythematosus: understanding of clinical features, genetic basis, and pathobiology of disease guides therapeutic strategies. Autoimmunity. 2006;39(6):433-44. https://doi.org/10.1080/08916930600886851
Duarte AA. Lúpus eritematoso. In: Duarte AA. Colagenoses e a dermatologia. 2ª ed. São Paulo: Dilivros; 2012.
Urman JD, Lowenstein MB, Abeles M, Weinstein A. Oral mucosal ulceration in systemic lupus erythematosus. Arthritis Rheum. 1978;21(1):58-61. https://doi.org/10.1002/art.1780210110
Saleh D, Crane JS. Tumid lupus erythematosus. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2019 [acesso em 15 abr. 2019]. Disponível em: https://www.ncbi.nlm.nih.gov/books/NBK482515/
Petersen MP, Möller S, Bygum A, Voss A, Bliddal M. Epidemiology of cutaneous lupus erythematosus and the associated risk of systemic lupus erythematosus: a nationwide cohort study in Denmark. Lupus. 2018;27(9):1424-30. https://doi.org/10.1177/0961203318777103
Jarrett P, Thornley S, Scragg R. Ethnic differences in the epidemiology of cutaneous lupus erythematosus in New Zealand. Lupus. 2016;25(13):1497-502. https://doi.org/10.1177/0961203316651745
Sato EI, Bonfá ED, Costallat LTL, Silva NA, Brenol JC, Santiago MB, et al. Consenso brasileiro para o tratamento do lúpus eritematoso sistêmico (LES). Rev Bras Reumatol. 2002;42(6):362-70. https://doi.org/10.1590/S0482-50042008000400002
Martins GS, Rocha C, Esteves IM, Maia JL, Arruda LM, Zanatta LH, et al. Avaliação da prevalência de alterações dermatológicas em pacientes com lúpus eritematoso sistêmico. Rev Med Saúde Bras. 2014;2(3):125-32.
McDaniel B, Tanner LS. Discoid lupus erythematosus. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2019 [acesso em 15 abr. 2019]. Disponível em: https://www.ncbi.nlm.nih.gov/books/NBK493145/
Barbosa WS, Rodarte CM, Guerra JG, Maciel VG, Fleury Júnior LF, Costa MB. Lúpus eritematoso sistêmico bolhoso: diagnóstico diferencial com dermatite herpetiforme. An Bras Dermatol. 2011;86(4):92-5. https://doi.org/10.1590/S0365-05962011000700024
Padrão EM, Teixeira LF, Maruta CW, Aoki V, Silva AS, Kim EI, et al. Bullous systemic lupus erythematosus–a case report. Autopsy Case Rep. 2019;9(1):344-6. https://doi.org/10.4322/acr.2018.069
Mascote Márquez MDR. Determinación de las características clínicas, inmunológicas y epidemiológicas del lupus eritematoso sistémico en el servicio de Medicina Interna del Hospital Eugenio Espejo de la ciudad de Quito en el periodo comprendido desde enero 2015 hasta diciembre del 2017 [tese]. Quito: Pontificia Universidad Católica del Ecuador. Facultad de Medicina; 2018 [aceso em 25 abr. 2019]. Disponivel em: http://repositorio.puce.edu.ec/handle/22000/15393
Laurinaviciene R, Sandholdt LH, Bygum A. Drug-induced cutaneous lupus erythematosus: 88 new cases. Eur J Dermatol. 2017;27(1):28-33. https://doi.org/10.1684/ejd.2016.2912
Nascimento LL, Vasconcellos MR. Coexistence of chronic cutaneous lupus erythematosus and frontal fibrosing alopecia. An Bras Dermatol. 2018;93(2):274-6. https://doi.org/10.1590/abd1806-4841.20186992
Speeckaert R, van Geel N. Vitiligo and lupus: more similarities than meets the eye. Br J Dermatol. 2017;177(5):1161-2. https://doi.org/10.1111/bjd.15960
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2021 Revista da Faculdade de Ciências Médicas de Sorocaba
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Os autores no momento da submissão transferem os direitos autorais, assim, os manuscritos publicados passam a ser propriedade da revista.
O conteúdo do periódico está licenciado sob uma Licença Creative Commons 4.0, esta licença permite o livre acesso imediato ao trabalho e que qualquer usuário leia, baixe, copie, distribua, imprima, pesquise ou vincule aos textos completos dos artigos, rastreando-os para indexação, passá-los como dados para o software, ou usá-los para qualquer outra finalidade legal.