Prevalência e fatores associados à dislipidemia em um município do Espírito Santo, Brasil

Patricia Silva Cunha; Ronaldo José Faria; Patrícia Silva Bazoni; Josiane Pezzin; Nicole Milato da Silva Gonçalves; Jéssica Barreto Ribeiro dos Santos; Michael Ruberson Ribeiro da Silva

doi:10.23925/1984-4840.2025v27a3

Authors

Patricia Silva Cunha Universidade Federal do Espírito Santo (Ufes)
Ronaldo José Faria Universidade Federal do Espírito Santo (Ufes)
Patrícia Silva Bazoni Universidade Federal do Espírito Santo (Ufes)
Josiane Pezzin Universidade Federal do Espírito Santo (Ufes)
Nicole Milato da Silva Gonçalves Universidade Federal do Espírito Santo (Ufes)
Jéssica Barreto Ribeiro dos Santos Universidade Federal do Espírito Santo (Ufes)
Michael Ruberson Ribeiro da Silva Universidade Federal do Espírito Santo (Ufes)

DOI:

https://doi.org/10.23925/1984-4840.2025v27a3

Keywords:

Hyperlipidemias, Prevalence, Risk Factors, Cross-Sectional Studies

Abstract

Objective: To identify the prevalence and factors associated with dyslipidemia in adults living in the city of Alegre, Espírito Santo. Methods: A cross-sectional study was conducted in the city of Alegre, Brazil. Descriptive analyses were performed based on the frequency distributions of sociodemographic characteristics, health profile, pre-existing diseases, medication use, and quality of life. Factors associated with dyslipidemia were analyzed using Poisson regression with robust variance. Results: A total of 694 individuals were interviewed, of whom 174 (25.1%) reported having been diagnosed with dyslipidemia. The majority of participants were women (72.9%), self-declared white (47.5%), lived in the city center (69.6%), and were married (43.3%). Factors associated with dyslipidemia included older age, physical activity, polypharmacy, and having more than two comorbidities. Conclusion: Guidance from health professionals regarding physical activity, healthy eating, and medical monitoring is essential,
as high levels of total cholesterol, triglycerides, and LDL are evidenced as risk factors for cardiovascular diseases.

Downloads

Download data is not yet available.

Metrics

No metrics found.

References

Araújo LPG, Glauce SS, Dias PLR, Nepomuceno RM, Cola CSD. Principais fatores de risco para o acidente vascular encefálico e suas consequências: uma revisão de literatura. REINPEC. 2017;3(1):283-96. doi: 10.20951/2446-6778/v3n1a20.

Faludi AA, Izar MCO, Saraiva JFK, Chacra APM, Bianco HT, Afiune A, et al. Atualização da Diretriz Brasileira de Dislipidemias e Prevenção da Aterosclerose – 2017. Arq Bras Cardiol. 2017;109(2):1–76. doi: 10.5935/abc.20170121.

Nogueira de Sá ACMG, Gomes CS, Moreira AD, Velasquez-Melendez G, Malta DC. Prevalência e fatores associados ao diagnóstico autorreferido de colesterol alto na população adulta brasileira: Pesquisa Nacional de Saúde 2019. Epidemiol Serv Saúde. 2022;31(spe1):e2021380. doi: 10.1590/SS2237-9622202200002.especial.

Calmarza CP, Civeira Murillo F. Protocolo diagnóstico de las dislipidemias. Medicine Progr Form Méd Contin Acred. 2013;11(40): 2424–8. doi: 10.1016/S0304-5412(13)70640-1.

Oliveira LB, Carvalho IB, Dourado CSME, Dourado JCL, Nascimento MO. Prevalência de dislipidemias e fatores de risco associados. J Health Biol Sci. 2017; 5(4):320-5. doi: 10.12662/2317-3076jhbs.v5i4.1306.p320-325.2017.

Silva EA, Fernandes DR, Sandoval AC, Terra Júnior AT. O uso das estatinas no tratamento da dislipidemia e o mecanismo da biossíntese do colesterol. Rev Cient FAEMA. 2018;9:597-602. doi: 10.31072/rcf.v9iedesp.606.

World Medical Association. World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects. JAMA. 2013;310(20):2191-4. doi: 10.1001/jama.2013.281053.

Instituto Brasileiro de Geografia e Estatística. Censo Demográfico 2010 [Internet]. 2010 [acesso em 24 jan. 2024]. Disponível em: https://censo2010.ibge.gov.br/sinopse/index.php?- dados=29&uf=32.

Silva PLN, Bianchini ZM, Dias AJR. Amostragem: teoria e prática usando R [Internet]. Rio de Janeiro: [editora desconhecida]; 2021 [acesso em 5 set. 2023]. Disponível em: https://amostragemcomr.github.io/livro/index.html.

Noubiap JJ, Bigna JJ, Nansseu JR, Nyaga UF, Balti EV, Echouffo-Tcheugui JB, et al. Prevalence of dyslipidaemia among adults in Africa: a systematic review and meta-analysis. Lancet Global Health. 2018;6(9):e998–e1007. doi: 10.1016/S2214-109X(18)30275-4.

Mateo-Gallego R, Gracia-Rubio I, Garza MC, Cebollada A, Pérez-Calahorra S, Bayona-Sánchez A, et al. The impact of the COVID-19 pandemic in diabetes and dyslipidemia management in a Spanish region: a retrospective study of the Aragon population. Front Med (Lausanne). 2023;10:1191026. doi: 10.3389/fmed.2023.1191026.

Brasil. Ministério da Saúde. Departamento de Gestão e Incorporação de Tecnologias e Inovação em Saúde. Protocolo Clínico e Diretrizes Terapêuticas da Dislipidemia: prevenção de eventos cardiovasculares e pancreatite. Brasília (DF): Ministério da Saúde; 2020 [acesso em 10 set. 2023]. Disponível em: https://www.gov.br/conitec/ptbr/midias/protocolos/publicacoes_ms/pcdt_dislipidemia_prevencaoeventoscardiovascularesepancreatite_isbn_18-08-2020.pdf.

Rhee EJ, Kim HC, Kim JH, Lee EY, Kim BJ, Kim EM, et al. 2018 Guidelines for the management of dyslipidemia. Korean J Intern Med. 2019;34(4):723-71. doi: 10.3904/kjim.2019.188.

Pirillo A, Casula M, Olmastroni E, Norata GD, Catapano AL. Global epidemiology of dyslipidaemias. Nat Rev Cardiol. 2021;18(10):689-700. doi: 10.1038/s41569-021-00541-4.

Moraes SA, Checchio MV, Freitas ICM. Dislipidemia e fatores associados em adultos residentes em Ribeirão Preto, SP: resultados do Projeto EPIDCV. Arq Bras Endocrinol Metab. 2013;57:691–701. doi: 10.1590/S0004-27302013000900004.

Atella V, Piano Mortari A, Kopinska J, Belotti F, Lapi F, Cricelli C, et al. Trends in age-related disease burden and healthcare utilization. Aging Cell. 2018;18(1):e12861. doi: 10.1111/acel.12861.

Wengrofsky P, Lee J, Makaryus AN. Dyslipidemia and its role in the pathogenesis of atherosclerotic cardiovascular disease: implications for evaluation and targets for treatment of dyslipidemia based on recent guidelines. In: McFarlane SI, editor. Dyslipidemia. London: IntechOpen; 2019. doi: 10.5772/intechopen.85772.

Ali N, Samadder M, Kathak RR, Islam F. Prevalence and factors associated with dyslipidemia in Bangladeshi adults. PLOS ONE. 2023;18(1):e0280672. doi: 10.1371/journal.pone.0280672.

Nie F, Wang Z, Zeng Q, Guan H, Yang J, Luo P, et al. Health behaviors and metabolic risk factors are associated with dyslipidemia in ethnic Miao Chinese adults: the China multi-ethnic cohort study. BMC Public Health. 2021;21(1):851. doi: 10.1186/s12889-021-10871-0.

Pereira LP, Sichieri R, Segri NJ, Silva RMVG, Ferreira MG. Dislipdemia autorreferida na região Centro-Oeste do Brasil: prevalência e fatores associados. Ciênc Saúde Coletiva. 2015;20(6):1815–24. doi: 10.1590/1413-81232015206.16312014.

Crochemore-Silva I, Knuth AG, Wendt A, Nunes BP, Hallal PC, Santos LP, et al. Physical activity during the COVID-19 pandemic: a population-based cross-sectional study in a city of South Brazil. Ciênc Saúde Coletiva. 2020;25(11):4249-58. doi: 10.1590/1413-812320202511.29072020.

Pitanga FJG, Beck CC, Pitanga CPS. Atividade física e redução do comportamento sedentário durante a pandemia do coronavírus. Arq Bras Cardiol. 2020;114(6):1058-60. doi: 10.1590/1413-812320202511.29072020.

Martínez-Montesinos L, Rivera-Caravaca JM, Agewall S, Soler E, Lip GYH, Marín F, et al. Polypharmacy and adverse events in atrial fibrillation: Main cause orreflection of multimorbidity? Biomed Pharmacother. 2023;158:114064. doi: 10.1016/j.biopha.2022.114064.

Bazoni PS, Faria RJ, Cordeiro FJR, Timóteo ÉDS, Silva AM, Horsth AL, et al. Self-medication during the COVID-19 pandemic in Brazil: findings and implications to promote the rational use of medicines. Int J Environ Res Public Health. 2023;20(12):6143. doi: 10.3390/ijerph20126143.

Silva AM, Horsth AL, Timóteo ÉDS, Faria RJ, Bazoni PS, Meira EF, et al. Use of medicinal plants during COVID-19 pandemic in Brazil. Sci Rep. 2023;13:16558. doi: 10.1038/s41598-023-43673-y.

Santos RM, Silva EBS, Rodiguero G, Acrani GO, Kasperavicius JP, Fernandes JGP, et al. Prevalência de dislipidemia e sua relação com condições sociodemográficas, de saúde e de comportamento entre usuários da atenção primária à saúde. Braz J Health Rev. 2022;5(2):7353–70. doi: 10.34119/bjhrv5n2-295.

Kang P, Shin HY, Kim KY. Association between dyslipidemia and mercury exposure in adults. Int J Environ Res Public Health. 2021;18(2):775. doi: 10.3390/ijerph18020775.