Impact of COVID-19 on postoperative mortality in patients with proximal femoral fractures

a systematic review with meta-analysis

Authors

  • Daniel Campos de Jesus Pontifícia Universidade Católica de Campinas
  • Joanne Conçeição Martins Aragão Costa Dias Universidade Tiradentes
  • Mariana Camargo Cerri Pontifícia Universidade Católica de Campinas
  • Livia Faria Moretti Pontifícia Universidade Católica de Campinas
  • Cintia Kelly Bittar Pontifícia Universidade Católica de Campinas
  • Jose Alexandre Mendonça Pontifícia Universidade Católica de Campinas

DOI:

https://doi.org/10.23925/1984-4840.2025v27a10

Keywords:

COVID-19, Mortality, Proximal Femoral Fractures, Hospitalization, Postoperative Care

Abstract

Objective: This systematic review and meta-analysis aims to characterize the impact of the COVID-19 pandemic on postoperative mortality rates in patients with proximal femoral fractures. Methodology: A systematic review and meta-analysis were performed using Cochrane tools, employing a PICO strategy (Patient or Problem: Femur fracture with COVID-19; Intervention: Surgery; Control or Comparison: Femur fracture without COVID-19; Outcomes: Overall mortality and length of hospital stay; Time: Minimum follow-up of six months. Results: After applying the inclusion and exclusion criteria, eight studies were deemed eligible for meta-analysis from an initial pool of 264 articles. These studies collectively involved 10,902 participants. The overall mortality rate was found to be 28.2% among patients with COVID-19, in contrast to 8.25% among those without the infection. A significantly higher proportion of deaths was observed among COVID-19 positive patients compared to their negative counterparts, yielding an overall odds ratio (OR) of 4.93 (95% CI: 2.79 - 8.71; p <0.001). Conclusion: The findings underscore the profound impact of COVID-19 on the mortality of patients undergoing surgery for hip fractures, indicating an almost five-fold increased risk of death. This data underscores the severity of the infection within an already vulnerable population.

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Published

2025-06-18

How to Cite

Jesus, D. C. de, Dias, J. C. M. A. C., Cerri , M. C., Moretti, L. F., Bittar , C. K., & Mendonça, J. A. . (2025). Impact of COVID-19 on postoperative mortality in patients with proximal femoral fractures: a systematic review with meta-analysis. Revista Da Faculdade De Ciências Médicas De Sorocaba, 27(Fluxo contínuo), e70212. https://doi.org/10.23925/1984-4840.2025v27a10

Issue

Vol. 27 No. Fluxo contínuo (2025)

Section

Systematic review

Categories

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