Anticipatory nausea and vomiting: key points
Keywords:
nausea, anticipatory vomiting, antineoplastic agents, adaptation psychological.Abstract
ABSTRACT Nausea and vomiting remain an important problem during radiotherapy or chemotherapy based regimens. Management of anticipatory nausea and vomiting (ANV), apparently caused by conditioning mechanisms, has seen little improvement. This conditioning model proposes that stimuli unrelated to treatment are associated by the patient with acute and delayed N&V caused by consecutive chemo cycles, eliciting, even before the next cycle, N&V. In systematic reviews prevalence rates go as high as 30%. In our practical experience, the prevalence falls around 40%. Some predisposing factors have been proposed, such as age, the occurrence of N&V, sweating or fatigue after the last cycle of CT, as well as a predisposition for motion sickness. Preventing ANV is the best available management approach, since, once established, ANV seems to be resistant to all pharmacological resources available. Behavioral techniques remain the standard of care in ANV.Downloads
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