Infecção por Helicobacter pylori em pacientes com queixas dispépticas

Thiago Soares Gondim Medeiros; José Miguel Luz Parente; Cintia Maria de Melo Mendes; Carmen Viana Ramos; Joyce Lopes Macedo; Luiza Marly Freitas de Carvalho; Marta Maria da Silva Lira Batista; Maria do Carmo de Carvalho e Martins

doi:10.23925/1984-4840.2024v26a9

Authors

Thiago Soares Gondim Medeiros Centro Universitário UNINOVAFAPI
José Miguel Luz Parente Universidade Federal do Piauí (UFPI). Departamento de Clínica Geral
Cintia Maria de Melo Mendes Centro Universitário Santo Agostinho
Carmen Viana Ramos Secretaria da Saúde do Estado do Piauí. Maternidade Dona Evangelina Rosa
Joyce Lopes Macedo Universidade Federal do Piauí (UFPI). Departamento de Biofísica e Fisiologia
Luiza Marly Freitas de Carvalho Centro Universitário Santo Agostinho
Marta Maria da Silva Lira Batista Universidade Federal do Piauí (UFPI). Hospital Universitário
Maria do Carmo de Carvalho e Martins Universidade Federal do Piauí (UFPI). Departamento de Biofísica e Fisiologia

DOI:

https://doi.org/10.23925/1984-4840.2024v26a9

Keywords:

Helicobacter Infections, Dyspepsia, Urease, Endoscopy, Gastrointestinal

Abstract

Objective: To determine the frequency of Helicobacter pylori infection in patients with dyspeptic complaints and to assess the agreement between urease test results and histopathological examination in the diagnosis of infection. Methods: Ob[1]servational, cross-sectional and descriptive study, based on the results of the urease test, histopathological examination and endoscopic report of patients undergoing upper digestive endoscopy (EDA) at a University Hospital in the city of Teresina, Piauí. Results: The sample consisted of 300 patients, mostly women, with a mean age of 53.93 years. The urease test was positive in 34% of the exams and the histopathological test in 55%. The main justification for EDA was epigastric pain. The predominant alteration of the gastric mucosa in the histopathological examination was chronic gastritis, while in the endoscopic report the most common finding was erosive gastritis. The accuracy of the urease test in relation to the histo[1]pathological test was 76.33%, with a moderate level of agreement. On the other hand, the accuracy between UDE and histopathology was 67.7%, not showing agreement (kappa 0.05), according to the classification of the Kappa test by Landis and Koch (1977). Conclusion: The frequency of Helicobacter pylori infection was high. There was moderate agreement between diagnosis by urease and histopathological tests, but not between endoscopic and histopathological findings, with a greater presence of gastritis identified in the histopathological results.

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