Effect of prone position on oxygenation of patients with COVID-19 under invasive mechanical ventilation

Authors

  • Carolaine Ramos Martins Faculdade de Medicina de São José do Rio Preto (FAMERP). Programa de pós-graduação em Fisioterapia Hospitalar Adulto
  • Iuri Dheloi Oliveira de Lima Serviço de Fisioterapia em Terapia Intensiva/Fisioterapia. Hospital de Base
  • Lucas Lima Ferreira Universidade Estadual Paulista "Júlio de Mesquita Filho" (UNESP)

DOI:

https://doi.org/10.23925/1984-4840.2025v27a2

Keywords:

COVID-19, Prone Position, Physical Therapy Modalities, Respiratory Distress Syndrome

Abstract

Objective: To evaluate the behavior of the ventilation/perfusion ratio of patients with positive COVID-19 under mechanical ventilation (MV) after the prone position. Methodology: Quantitative, descriptive, retrospective research in an intensive care unit (ICU) COVID-19 from May to December 2020. Data were collected: age, sex, comorbidities, PaO2 collected from arterial blood gases, FiO2 collected of the mechanical ventilator at the time of blood gas collection to calculate the PaO2/FiO2 ratio. This relationship was calculated at the pre-prone, one-hour post-prone, six-hour post-prone, and four-hour post-supine moments. The time spent on MV (in days), the SAPS III score, the length of stay in the ICU (in days), and the outcomes of discharge or death in the unit were also collected. All data were collected from patients' electronic medical records. Results: 71 patients with a mean age of 58.7 ± 15.5 years, 60.5% male, were selected. The most prevalent comorbidity was arterial hypertension with 60.6%. The mean PaO2/FiO2 ratio before prone positioning was 113.11 mmHg, with a significant increase (p < 0.0001) of 91.97 mmHg after six hours in the prone position, with a mean duration of 19h46min ± 0h14min in the prone position. There was 55.5% of death among patients. Conclusion: The prone position caused a significant increase in oxygenation in patients
with COVID-19 under MV.

Author Biography

Lucas Lima Ferreira, Universidade Estadual Paulista "Júlio de Mesquita Filho" (UNESP)

Mestrando em Fisioterapia pela Faculdade de Ciências e Tecnologia (FCT) da Universidade Estadual Paulista "Júlio de Mesquita Filho" (UNESP), campus de Presidente Prudente; Especialista em Fisioterapia Clínica pelo Centro Universitário de São José do Rio Preto (UNIRP); Especialista em Fisioterapia Hospitalar pela Faculdade de Medicina de São José do Rio Preto (FAMERP); Graduado em Fisioterapia pela Fundação Educacional de Fernandópolis (FEF).

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Published

2025-04-02

How to Cite

Martins, C. R., Lima, I. D. O. de, & Ferreira, L. L. (2025). Effect of prone position on oxygenation of patients with COVID-19 under invasive mechanical ventilation. Revista Da Faculdade De Ciências Médicas De Sorocaba, 27(Fluxo contínuo), e67085. https://doi.org/10.23925/1984-4840.2025v27a2

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