Henoch-Schönlein purpura in adult

Authors

  • Jorge Luiz de Carvalho Mello Universidade do Vale do Sapucaí (UNIVAS), Faculdade de Medicina – Pouso Alegre (MG), Brasil.
  • Luis Paulo Cachola Gallo Universidade do Vale do Sapucaí (UNIVAS), Faculdade de Medicina – Pouso Alegre (MG), Brasil. http://orcid.org/0000-0002-5021-9030
  • Kayane Ridolfi Carvalho Universidade do Vale do Sapucaí (UNIVAS), Faculdade de Medicina – Pouso Alegre (MG), Brasil. http://orcid.org/0000-0002-4403-4275
  • Juliana Monroe Silva Hospital das Clínicas Samuel Libânio (FUVS) – Pouso Alegre (MG), Brasil. http://orcid.org/0000-0001-8151-8685
  • Sebastião Jupiaçara Guimarães Universidade do Vale do Sapucaí (UNIVAS), Faculdade de Medicina – Pouso Alegre (MG), Brasil. http://orcid.org/0000-0002-5441-8256
  • Carolina Fernandes Pereira Hospital das Clínicas Samuel Libânio (FUVS) – Pouso Alegre (MG), Brasil. http://orcid.org/0000-0002-7567-6983

DOI:

https://doi.org/10.23925/1984-4840.2018v20i3a10

Keywords:

Schoenlein-Henoch purpura, vasculitis, leukocytoclastic, cutaneous, vascular diseases

Abstract

Henoch-Schönlein purpura (HSP) is a vasculitis characterized by the deposit of IgA causing a leukocytoclastic reaction. Its etiology is not fully understood. It mainly affects children, and the involvement in adults is usually rarer and with worse prognosis. The most affected sites make up a tetrad: skin, joints, gastrointestinal tract and kidneys. The diagnosis is clinical, with the majority of patients presenting elevated serum IgA, and skin biopsy reveals a leukocytoclastic vasculitis. It usually is a benign and self-limiting disease, with supportive therapy being the basis of treatment along with rest and analgesia, and the use of corticosteroids in more intense cases. We reported the case of the disease in a 46-year-old male subject, admitted with palpable purpura, proteinuria, elevated serum IgA level and leukocytoclastic vasculitis on cutaneous biopsy. He was treated with corticosteroid therapy, evolving with significant improvement of the condition.

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Author Biographies

Jorge Luiz de Carvalho Mello, Universidade do Vale do Sapucaí (UNIVAS), Faculdade de Medicina – Pouso Alegre (MG), Brasil.

Professor de Clínica Médica da Universidade do Vale do Sapucaí

Chefe do Serviço de Clínica Médica do Hospital das Clínicas Samuel Libânio em Pouso Alegre-MG

Luis Paulo Cachola Gallo, Universidade do Vale do Sapucaí (UNIVAS), Faculdade de Medicina – Pouso Alegre (MG), Brasil.

In memoriam

Kayane Ridolfi Carvalho, Universidade do Vale do Sapucaí (UNIVAS), Faculdade de Medicina – Pouso Alegre (MG), Brasil.

Acadêmica de Medicina da Universidade do Vale do Sapucaí

Juliana Monroe Silva, Hospital das Clínicas Samuel Libânio (FUVS) – Pouso Alegre (MG), Brasil.

Médica residente em Clínica Médica do Hospital das Clínicas Samuel Libânio

Sebastião Jupiaçara Guimarães, Universidade do Vale do Sapucaí (UNIVAS), Faculdade de Medicina – Pouso Alegre (MG), Brasil.

Professor Titular de Clínica Médica da Universidade do Vale do Sapucaí

Carolina Fernandes Pereira, Hospital das Clínicas Samuel Libânio (FUVS) – Pouso Alegre (MG), Brasil.

Médica Residente em Clínica Médica do Hospital das Clínicas Samuel Libânio

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Published

2018-12-03

How to Cite

1.
Mello JL de C, Gallo LPC, Carvalho KR, Silva JM, Guimarães SJ, Pereira CF. Henoch-Schönlein purpura in adult. Rev. Fac. Ciênc. Méd. Sorocaba [Internet]. 2018Dec.3 [cited 2024Dec.18];20(3):174-7. Available from: https://revistas.pucsp.br/index.php/RFCMS/article/view/33097

Issue

Vol. 20 No. 3 (2018)

Section

Case Report

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