Acute calculous cholecystitis as manifestation in extraintestinal patient with Crohn’s disease: case report

Authors

  • Luilson Geraldo Coelho Júnior Universidade Federal do Espírito Santo (UFES), Hospital Universitário Cassiano Antonio Moraes (HUCAM) - Vitória (ES), Brasil.
  • Brenno Vinicius Porto Lima Faculdade Atenas, Medicina – Paracatu (MG), Brasil.
  • Danilo Fossalusa Minari Hospital Heliópolis – São Paulo (SP), Brasil.
  • Marcos Paulo Borges Mendanha Universidade de Brasília (UnB), Hospital Universitário de Brasília – Brasília (DF), Brasil.
  • Bernard Moreira Oliveira Faculdade Atenas, Medicina – Paracatu (MG), Brasil.
  • Hamilton Alexandre Grosmann Barbosa Faculdade Atenas, Medicina – Paracatu (MG), Brasil.
  • Adão Jair de Souza Faculdade Atenas, Medicina – Paracatu (MG), Brasil.

DOI:

https://doi.org/10.23925/1984-4840.2018v20i2a10

Keywords:

, inflammatory bowel diseases, Crohn disease, cholecystitis, cholelithiasis

Abstract

Crohn’s disease is an inflammatory bowel disease of unknown etiology that affects the gastrointestinal tract, and it may attack other organs, including the gallbladder. Among the hepatobiliary manifestations, patients may have cholecystitis, cholelithiasis, cholangitis. The association between Crohn’s disease and gallstone disease is well established: these patients are more likely to develop gallstones because of changes in the composition of bile and the reduced motility of the gallbladder. We describe a case in which a patient with Crohn’s disease showed cholelithiasis.

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

References

Teixeira, MG. Tratamento cirúrgico da doença de Crohn [tese de livre-docência]. São Paulo: Faculdade de Medicina, Universidade de São Paulo; 2000.

Fiocchi C. Inflammatory bowel disease: etiology and pathogenesis. Gastroenterology. 1998;115(1):182-205. https://doi.org/10.1016/S0016-5085(98)70381-6

Langholz E, Munkholm P, Krasilnikoff PA, Binder V. Inflammatory bowel diseases with onset in childhood. Clinical features, morbidity, and mortality in a regional cohort. Scand J Gastroenterol. 1997;32:139-47. https://doi.org/10.3109/00365529709000184

Kirschner BS. Differences in the management of inflammatory bowel disease in children and adolescents compared to adults. Neth J Med. 1998;53(6):S13-8.

Parente F, Pastore L, Bargiggia S, Cucino C, Greco S, Molteni M, et al. Incidence and risk factors for gallstones in patients with inflammatory bowel disease: a large case-control study Hepatology. 2007;45(5):1267-74. https://doi.org/10.1002/hep.21537

Gizard E, Ford AC, Bronowicki JP, Peyrin-Biroulet L. Systematic review: the epidemiology of the hepatobiliary manifestations in patients with inflammatory bowel disease. Aliment Pharmacol Ther. 2014;40(1):3-15. https://doi.org/10.1111/apt.12794

Gisbert JP, Chaparro M, Esteve M. Review article: prevention and management of hepatitis B and C infection in patients with inflammatory bowel disease. Aliment Pharmacol Ther. 2011;33(6):619-33. https://doi.org/10.1111/j.1365-2036.2010.04570.x

Khan N, Abbas AM, Whang N, Balart LA, Bazzano LA, Kelly TN. Incidence of liver toxicity in inflammatory bowel disease patients treated with methotrexate: a meta-analysis of clinical trials. Inflamm Bowel Dis. 2012;18:359-67. https://doi.org/10.1002/ibd.21820

Levine JS, Burakoff R. Extraintestinal manifestations of inflammatory bowel disease. Gastroenterol Hepatol. 2011;7(4):235-41.

Kratzer W, Haenle MM, Mason RA, von Tirpitz C, Kaechele V. Prevalence of cholelithiasis in patients with chronic inflammatory bowel disease. World J Gastroenterol. 2005;11(39):6170-5. https://doi.org/10.3748/wjg.v11.i39.6170

Kangas E, Lehmusto P, Matikainen M. Gallstones in Crohn’s disease. Hepatogastroenterology. 1990;37(1):83-4.

Bargiggia S, Maconi G, Elli M, Molteni P, Ardizzone S, Parente F, et al. Sonographic prevalence of liver steatosis and biliary tract stones in patients with inflammatory bowel disease: study of 511 subjects at a single center. J Clin Gastroenterol. 2003;36(5):417-20.

Hutchinson R, Tyrrell PN, Kumar D, Dunn JA, Li JK, Allan RN. Pathogenesis of gall stones in Crohn’s disease: an alternative explanation. Gut. 1994;35(1):94-7.

Lapidus A, Einarsson C. Bile composition in patients with ileal resection due to Crohn’s disease. Inflamm Bowel Dis. 1998;4(2):89-94. https://doi.org/10.1002/ibd.3780040204

Lapidus A, Einarsson K. Effects of ileal resection on biliary lipids and bile acid composition in patients with Crohn’s disease. Gut. 1991;32(12):1488-91.

Lapidus A, Akerlund JE, Einarsson C. Gallbladder bile composition in patients with Crohn’s disease. World J Gastroenterol. 2006;12(1):70-4. https://doi.org/10.3748/wjg.v12.i1.70

Pereira SP, Bain IM, Kumar D, Dowling RH. Bile composition in inflammatory bowel disease: ileal disease and colectomy, but not colitis, induce lithogenic bile. Aliment Pharmacol Ther. 2003;17(7):923-33. https://doi.org/10.1046/j.1365-2036.2003.01529.x

Rutgeerts P, Ghoos Y, Vantrappen G, Fevery J. Biliary lipid composition in patients with nonoperated Crohn’s disease. Dig Dis Sci. 1986;31(1):27-32.

Brink MA, Slors JFM, Keulemans YCA, Mok KS, De Waart DR, Carey MC, et al. Enterohepatic cycling of bilirubin: a putative mechanism for pigment gallstone formation in ileal Crohn’s disease. Gastroenterology. 1999;116(6):1420-7. https://doi.org/10.1016/S0016-5085(99)70507-X

Parray FQ, Wani ML, Bijli AH, Thakur N, Irshad I, Nayeem-ul-Hassan. Crohn’s disease: a surgeon’s perspective. Saudi J Gastroenterol. 2011;17(1):6-15. https://doi.org/10.4103/1319-3767.74430

Wilkens R, Novak KL, Lebeuf-Taylor E, Wilson SR. Impact of intestinal ultrasound on classification and management of Crohn’s disease patients with inconclusive colonoscopy. Can J Gastroenterol Hepatol. 2015;2016 (Article ID8745972):1-9. https://doi.org/10.1155/2016/8745972

Published

2018-07-25

How to Cite

1.
Coelho Júnior LG, Lima BVP, Minari DF, Mendanha MPB, Oliveira BM, Barbosa HAG, Souza AJ de. Acute calculous cholecystitis as manifestation in extraintestinal patient with Crohn’s disease: case report. Rev. Fac. Ciênc. Méd. Sorocaba [Internet]. 2018Jul.25 [cited 2024Jul.18];20(2):107-9. Available from: https://revistas.pucsp.br/index.php/RFCMS/article/view/31688

Issue

Section

Case Report