Glomerulopatia por IgA com crescentes fibrocelulares e associada à psoríase: nefropatia psoriásica?

Rafael Naufel de Sá Rebelo; Rafael Yuri Sano; Nathália Figueiredo de Oliveira; Maria Almerinda Vieira Fernandes Ribeiro  Alves; Sérgio Ricardo Rocha de Araújo; Ronaldo D'Ávila

doi:10.23925/1984-4840.2021v23i3/4a9

Authors

Rafael Naufel de Sá Rebelo Pontifícia Universidade Católica de São Paulo. Faculdade de Ciências Médicas e da Saúde – Sorocaba (SP), Brasil. https://orcid.org/0000-0002-3123-3654
Rafael Yuri Sano Conjunto Hospitalar de Sorocaba – Sorocaba (SP), Brasil.
Nathália Figueiredo de Oliveira Conjunto Hospitalar de Sorocaba – Sorocaba (SP), Brasil.
Maria Almerinda Vieira Fernandes Ribeiro Alves Universidade Estadual de Campinas. Faculdade de Ciências Médicas – Campinas (SP), Brasil.
Sérgio Ricardo Rocha de Araújo Conjunto Hospitalar de Sorocaba – Sorocaba (SP), Brasil.
Ronaldo D'Ávila Pontifícia Universidade Católica de São Paulo. Faculdade de Ciências Médicas e da Saúde – Sorocaba (SP), Brasil.

DOI:

https://doi.org/10.23925/1984-4840.2021v23i3/4a9

Keywords:

glomerulonephritis IgA, psoriasis, arthritis, psoriatic, adalimumab, tumor necrosis factor inhibitors

Abstract

Some reports have showed a link among IgA glomerulonephritis and psoriasis and or use of anti-TNF drugs. We describe the case of a patient with psoriatic arthritis, in use of anti-TNF drugs for four years, who presented an IgA nephropathy aggravated by glomerular crescents at renal biopsy and renal failure requiring hemodialysis. After methylprednisolone IV and three months of oral corticosteroid therapy, there was a partial but significant improvement in renal function and proteinuria. Dialysis treatment was stopped and treatment with SGLT-2 inhibitors was started.

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